Proteomics is the investigation of all the proteins and their various modifications that make up a system in a cell, tissue or an organism. As proteins are viral parts of living organisms with many functions, so the proteomics is more beneficial to genomics, because of representing the actual condition of a cell.
At CAMB, the group is working on
- Enzymes, including amylases, proteinases, cellulases, polymerases etc, having industrial (food, textile, pharmaceutical, paper etc) and research importance, respectively. As microbes provide a potential replacement in absence or in insufficiency of human enzymes, so they can be easily produced in large quantities in a short period of time through genetic manipulation/s.
- Recombinant Proteins/Hormones/Growth Factor/s, including interferons, interleukins, cytokines etc. They are usually secreted by the cells and have a specific effect on the interactions and communications between the cells of immune system.
- Therapeutic Proteins, like Lectins, Thionins, RIPs, peptides etc., having anti bacterial, anti viral, anti fungal and anti cancer potential , serve to complement structural barrier against the infections, which still remains uncharted.
The Proteomics Group is mainly focusing on screening, isolation, purification, characterization, bioactivity and modification/s for their improvement and therapeutics, respectively. The group has a wonderful command and expertise in Micro/Molecular/Cell Biology, by using Cloning, Vector Construction, Expression, Mutation/s, Purification/s, Iso electric point (pI) determination for a protein, Immuno Blotting/s and Simple Sequence Repeats (SSR), studies/techniques, in microbes/cells and plants.
Provide testing facility for microbes/fungus, through microscopy, biochemical tests and PCR.